To take Carrasco's spot on the 25-man roster, right-hander Frank Herrmann was recalled from Triple-A Columbus.
Carrasco sat in front of his locker inside the Indians' clubhouse on Wednesday, wearing a look of frustration after his right arm refused to cooperate during a planned throwing session.
Carrasco still experienced some discomfort while throwing long toss and was unable to advance to a bullpen session as he hoped.
"I felt it a little bit," Carrasco said Wednesday. "And I was using my shoulder too much. I didn't want to hurt my shoulder, too, so I stopped throwing. I'll start doing my exercises and treatment and everything. I don't know anything about after that."
Carrasco, 24, exited his start on Sunday in Minnesota after three innings due to tightness in his throwing elbow. An MRI exam performed on his arm revealed no structural damage, but Carrasco will require more time to return to full strength.
Carrasco, who opened this season as the Tribe's No. 2 starter, is 1-1 with a 4.97 ERA through five starts this year.
"It's not bad," Indians manager Manny Acta said Wednesday. "We have to be careful with him, so we're just going to slow it down. We're happy with the MRI results. That's the best we can do with that situation."
Acta noted that once Carrasco was placed on the 15-day DL, the Indians would promote a reliever from the Minors to have an extra arm in the mix until Saturday. That extra arm became Herrmann.
The Indians announced on Thursday that top pitching prospect Alex White will get the call from Triple-A Columbus to start on Saturday.
White, 22, was Cleveland's top pick in the 2009 First-Year Player Draft, but the righty is not on the team's 40-man roster. A subsequent move will be needed to bring him to Cleveland. So far this season, White has gone 1-0 with a 1.90 ERA and 28 strikeouts in 23 2/3 innings through four starts with the Clippers.