Carrasco -- fresh off a rehab outing with Double-A Akron -- was activated from the 15-day disabled list for a start on Wednesday against the Rays. Indians manager Manny Acta said Carrasco has no restrictions after his bout with right elbow inflammation.
"He's good to go," Acta said on Tuesday.
Carrasco opened the season as Cleveland's No. 2 starter, but exited his start against the Twins on April 24 after three innings due to elbow discomfort. On Friday at Akron, the right-hander allowed four runs on four hits over 3 2/3 innings, during which he struck out three and walked three.
For the season, Carrasco is 1-1 with a 4.97 ERA in five starts for the Tribe.
The Indians optioned right-hander Frank Herrmann to Triple-A Columbus to make roster space for Carrasco. Herrmann was recalled on Tuesday but did not appear in Cleveland's 5-4 win over Tampa Bay.
Talbot, who has been sidelined with a right elbow strain since April 17, made a four-inning rehab start in extended Spring Training on Monday. Acta said Talbot -- the Tribe's fifth starter when the season opened -- logged 63 pitches without complaint at the team's training complex in Goodyear, Ariz.
"It went well," Acta said. "He threw all his pitches with no problems. He's going to come up here to Cleveland to be seen again by [head athletic trainer Lonnie Soloff]. We'll take his temperature and then he'll go down there and continue his rehab."
Acta was not sure where Talbot's next rehab appearance would be, but noted that the right-hander will likely need at least two more Minor League outings before rejoining the Major League staff. Talbot went 1-1 with a 1.46 ERA in two starts for Cleveland before landing on the 15-day DL.