De La Cruz was designated for assignment on Feb. 13 to vacate a spot on Cleveland's 40-man roster for recently-signed first baseman Casey Kotchman. The Indians signed Kotchman to a one-year contract worth $3 million earlier this month.
The 23-year-old De La Cruz spent last season with Double-A Akron -- his second year at that level in the Tribe's system. The lefty went 5-6 with a 4.19 ERA in 23 appearances, including 16 starts, in 2011 for the Aeros. De La Cruz struck out 95 and walked 57 over 86 innings.
Over the course of his six-year stay in the Indians' farm system, De La Cruz went 32-28 with a 4.21 ERA across 105 games (93 starts). Across 455 1/3 innings, the southpaw amassed 448 strikeouts against 247 walks.